Oligodendroglioma

Slow-growing tumor developing from brain white matter

What is this Condition?

Oligodendroglioma is a glial tumor originating from oligodendrocyte cells in the brain. Usually occurs in young adults in frontal or temporal lobes. IDH mutation and 1p/19q codeletion increase treatment response.

Symptoms

Epileptic seizures (most common first symptom)
Headache
Personality changes
Cognitive impairments
Motor weakness
Speech difficulties

Diagnosis Methods

MRI shows heterogeneous lesion containing calcification. Molecular pathological examination investigates IDH mutation and 1p/19q codeletion.

Treatment Methods

After maximal safe surgical resection, radiotherapy and chemotherapy (PCV or temozolomide) are applied based on grade and molecular markers.

Surgical Resection
Radiotherapy
PCV Chemotherapy
Temozolomide Treatment

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Popüler aramalar:

Doç. Dr. Özgür AKŞAN

Beyin ve Sinir Cerrahisi

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Oligodendroglioma Tedavisi | Doç. Dr. Özgür AKŞAN