Peripheral Nerve

Brachial Plexus and Thoracic Outlet Syndrome

Assoc. Prof. Özgür AkşanIssue 01October–December 2026 2 min read

Brachial Plexus and Thoracic Outlet Syndrome
In brachial plexus injuries, success rates are higher when nerve transfer surgery is performed within the first 12 months.
In brachial plexus injuries, success rates are higher when nerve transfer surgery is performed within the first 12 months.

Anatomy

The brachial plexus consists of the C5-T1 nerve roots; it emerges from the neck and extends to the armpit, providing innervation to the entire upper extremity.

Injury Types

Supraclavicular (upper type — Erb-Duchenne): C5-C6 involvement. Loss of shoulder abduction and external rotation, weakness in elbow flexion. Most commonly seen in motorcycle accidents.1,2

Infraclavicular (lower type — Klumpke): C8-T1 involvement. Weakness in the intrinsic muscles of the hand, may be accompanied by Horner syndrome.

Total plexus injury: Loss of all arm functions. Root avulsion (preganglionic) has the worst prognosis.3,4

Treatment

If there is no improvement, surgical exploration + nerve graft/transfer. In avulsion: nerve transfers (e.g., intercostal nerves → musculocutaneous nerve). In the late stage: tendon transfers, arthrodesis.

Thoracic Outlet Syndrome (TOS)

What is it?

It is a symptom complex that develops as a result of compression on the brachial plexus and/or subclavian vessels in the narrow passage between the neck and the armpit (thoracic outlet).

Types

Neurogenic TOS (95%): Nerve compression, pain in the arm, numbness, weakness.5 Generally seen in young women and people with long necks. Common after whiplash.

Venous TOS (3%): Subclavian vein thrombosis (Paget-Schroetter syndrome). Swelling and bruising in the arm.

Arterial TOS (2%): Subclavian artery compression. Coldness in the arm, loss of pulse, risk of embolisation.

Treatment

In neurogenic TOS, primarily physical therapy (posture correction, shoulder strengthening, scalene stretching).


→ Next page: S47 — Normal Pressure Hydrocephalus

The neurogenic type accounts for 95 percent of Thoracic Outlet Syndrome cases.
The neurogenic type accounts for 95 percent of Thoracic Outlet Syndrome cases.

Kaynaklar

  1. Kaiser R et al. Neurosurg Rev. 2020. PMID 30014280
  2. Soldado F et al. Hand Surg Rehabil. 2016. PMID 27117025
  3. Chuang DC. Semin Plast Surg. 2010. PMID 21286305
  4. Songcharoen P et al. J Hand Surg Am. 2001. PMID 11721251
  5. Masocatto NO et al. Rev Col Bras Cir. 2019. PMID 31859722
  6. de Azevedo FAS et al. Acta Ortop Bras. 2019. PMID 31798318
Doç. Dr. Özgür Akşan

Doç. Dr. Özgür Akşan

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