Spine Surgery

MISS vs. Open Surgery: Comparison and Indications

Assoc. Prof. Özgür AkşanIssue 01October–December 2026 2 min read

MISS vs. Open Surgery: Comparison and Indications
In the MISS method, the incision size is 1-3 cm, whereas in open surgery it is between 8-15 cm.
In the MISS method, the incision size is 1-3 cm, whereas in open surgery it is between 8-15 cm.
ParameterMISSOpen Surgery
Incision size1-3 cm8-15 cm
Muscle damageMinimalSignificant
Blood loss1LessMore
Hospital stay1,2ShorterLonger
Return to work2ShorterLonger
Infection risk2,3LowerHigher
CostHigher (technology)Lower
Learning curveLongStandard

Ideal Patients for MISS

MISS has indications for conditions such as disc herniation, spinal stenosis, Grade I-II spondylolisthesis, and trauma.4,5

Hybrid Approaches

In modern practice, hybrid approaches are frequently used: such as combinations of lateral interbody fusion (MISS) + posterior percutaneous screw (MISS) or anterior fusion (open) + posterior percutaneous screw (MISS). The goal is to use the best aspect of each technique.


→ Next page: S37 — Right Timing in Spine Surgery

The hospital stay after MISS is shorter compared to open surgery.
The hospital stay after MISS is shorter compared to open surgery.

Kaynaklar

  1. Yolcu YU et al. World Neurosurg. 2021. PMID 33276177
  2. McClelland S 3rd et al. J Neurosci Rural Pract. 2017. PMID 28479791
  3. Camacho JE et al. J Spine Surg. 2019. PMID 31380497
  4. Kumar A et al. J Craniovertebr Junction Spine. 2022. PMID 36263335
  5. Park J et al. Asian Spine J. 2020. PMID 33108835
Doç. Dr. Özgür Akşan

Doç. Dr. Özgür Akşan

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